Keith Knowlton is a skilled litigator with a passion for representing clients in the courtroom. He concentrates his practice on defending physicians, nurses, hospitals, nursing homes, pharmacies, and other health care providers in medical malpractice litigation. He handles matters in state and federal courts and has obtained defense verdicts in jury trials involving various medical specialties.

Keith attended Furman University where he received his B.A. in Political Science and was a four-year starter on Furman’s Rugby Team. He received his law degree at Cumberland School of Law at Samford University. While in law school, he was a member of Cumberland’s nationally-ranked National Trial Team, winning numerous national and regional team competitions as well as individual awards for outstanding advocacy.

Before attending law school, Keith and his wife, Rachel, served on the mission field in China. Keith currently serves as a deacon at Downtown Presbyterian Church and remains passionate about serving exchange students and other foreign nationals residing in our community. Keith enjoys spending time with his wife and three young children, and before sunrise he can usually be found at the Caine Halter YMCA or on the Swamp Rabbit Trail.


  • Furman University,
    Bachelor of Arts, 2008
  • Cumberland School of Law,
    Juris Doctor, 2013


  • South Carolina, 2013
  • United States District Court for the District of South Carolina

Professional Recognition

  • Best Lawyers in America, Medical Malpractice Law – Defendants, 2018-2020

Secured a voluntary dismissal of a radiologist who was alleged to have misread post-operative x-ray studies by failing to recognize misplacement or malalignment of surgical screws placed in a spinal fusion procedure, which allegedly resulted in severe pain, suffering, subsequent surgery and permanent injuries caused by nerve root impingement. The defense established that the studies in question were interpreted appropriately and, further, that there were no clinical indications at the time in question to suggest recommendation of definitive studies. No settlement was paid in exchange for the dismissal of the defendant radiologist and practice.

Ashby Davis, Keith Knowlton

Obtained a defense verdict for a family physician sued in a medical malpractice case in which the plaintiff alleged the physician failed to timely diagnose a parosteal osteosarcoma, a type of bone cancer, in a 28-year old female patient, who eventually died despite a leg amputation and five rounds of chemotherapy. At trial, the defense showed that the family physician followed the standard of care by properly addressing the patient’s leg pain and elevated lab values, which led to her diagnosis. The defense offered an expert witness in oncology, who testified that the patient’s cancer was incurable regardless of when the diagnosis was made. The jury returned a verdict for the defendants.

Ashby Davis, Keith Knowlton

Obtained a defense verdict for a cardiologist sued for medical malpractice and wrongful death after his patient died of a heart attack following an abnormal nuclear stress test. The plaintiff alleged that the cardiologist failed to timely notify the patient of his test results and admit him to the hospital. At trial, the defense highlighted the fact that the patient chose to leave the office after the nuclear stress test without seeing the cardiologist. The defense also offered two expert witnesses who explained that this patient’s sudden demise was unpredictable and improbable, particularly when the patient had been asymptomatic. The jury returned a verdict for the cardiologist.

Ashby Davis, Keith Knowlton

Obtained a defense verdict for an obstetrician who was sued in a medical malpractice case where the plaintiff alleged that the obstetrician applied excessive traction to the baby’s head to resolve a shoulder dystocia during delivery, causing a permanent brachial plexus injury. At trial, the defense offered two expert witnesses, including one of the nation’s leading experts on shoulder dystocia, who testified that the obstetrician followed the proper protocol to resolve the dystocia, and the injury was the result of the internal forces of the mother occurring during the dystocia. The jury returned a verdict for the defendant.

Ashby Davis, Keith Knowlton